Erythrocyte Glucose-6-phosphate Dehydrogenase Activity in Klinefelter's Syndrome

INHIBITION OF HUMAN ERYTHROCYTE GLUCOSE 6-PHOSPHATE DEHYDROGENASE ACTIVITY BY DEHYDROEPIANDROSTERONE AND RELATED STEROIDS.

The inhibitory effects of several steroids on G6PD activity using intact erythrocytes are reported. Incubation of whole blood with dehydroepiandrosterone (DHEA) resulted in 42% and 12% inhibition in the enzyme activity in the presence and absence of oxygen, respectively. Addition of epinephrine and/or aminophylline into the incubation medium caused further enzyme inhibition suggesting a po...

incidence of erythrocyte glucose-6-phosphate- dehydrogenase deficiency

in a survey carried out to establish the incidence of erythrocyte glucose­ 6-phosphate-dehydrogenase deficiency, 738 professional blood donors of tehran were examined. the fluorescent spot technique was used for screening and qualitative determination of g-6-pd in erythrocytes. this technique was compared with other methods of g-6-pd enzyme assay and proved to be very reliable. qualitative enzy...

the effect of lead on erythrocyte glucose-6-phosphate dehydrogenase activity in rats

conclusions the results of this study showed that exposure to lead increased the activity of g6pd in the rat erythrocytes, perhaps resulting in an up regulation of the enzyme to detoxify lead. materials and methods in this study 14 albino rats were divided into two groups of seven animals. the treated group was exposed to 2% lead acetate in the drinking water during eight weeks. the control gro...

Inhibition of Human Erythrocyte Glucose 6-Phosphate Dehydrogenase by Cadmium, Nickel and Aluminium

inhibition of human erythrocyte glucose 6-phosphate dehydrogenase activity by dehydroepiandrosterone and related steroids.

the inhibitory effects of several steroids on g6pd activity using intact erythrocytes are reported. incubation of whole blood with dehydroepiandrosterone (dhea) resulted in 42% and 12% inhibition in the enzyme activity in the presence and absence of oxygen, respectively. addition of epinephrine and/or aminophylline into the incubation medium caused further enzyme inhibition suggesting a possibl...